With the recent investment of more donor resources and WHO’s updated chemoprevention guidelines in June 2022, more countries are now implementing Perennial Malaria Chemoprevention (PMC). The Plus Project, funded by Unitaid, has supported the co-design, preparation, and now implementation of PMC in four countries: Benin, Cameroon, Cote d’Ivoire, and Mozambique. As a part of this work, the project has developed supportive supervision strategies and checklists in collaboration with NMCP partners. This document provides a high-level overview of the supportive supervision of PMC. Please also see the PMC supportive supervision checklist.