THE PLUS PROJECT
REDUCING MORBIDITY AND MORTALITY DUE TO MALARIA AND ANEMIA IN CHILDREN UNDER 2
About the project
The Plus Project is a 4.25-year Unitaid-funded project that has co-designed and piloted, and is in the process of evaluating, country-adapted models of Perennial Malaria Chemoprevention (PMC) – the recent WHO recommendation which includes what was previously called Intermittent Preventive Treatment in infants (IPTi) using sulfadoxine-pyrimethamine (SP) in four focus countries: Benin, Cameroon, Côte d’Ivoire, and Mozambique. Underpinning these PMC pilots is training, routine monitoring, supervision, and community engagement activities integrated into existing country systems.
The project is conducting a robust package of evaluations to generate evidence aimed at accelerating the adoption and scale-up of PMC in the project countries and other malaria-endemic countries of sub-Saharan Africa. Research studies include policy receptivity, process, impact, and economic evaluations, as well as SP suitability studies. The project is also conducting limited research in the Democratic Republic of the Congo, Ghana, and Zambia related to policy adoption, economic modeling, and SP resistance mapping to generate additional evidence for these countries and beyond.
The Plus Project will share learnings from implementation experience and research evidence to help countries decide if and how to use PMC as part of their malaria chemoprevention strategies. This includes supporting the PMC Community of Practice and rolling out a variety of external communications activities, such as quarterly bulletins, webinars, conference presentations, publications, and project website. The project has also helped to establish country advisory groups or technical working groups in project countries that are MoH-led and meet regularly to review PMC implementation and research progress, discuss challenges, and support the sustainability and scale of PMC.
WHY ARE WE EXCITED?
The project’s approach to collaborative design and decision making provides flexibility to National Malaria Programs to adapt PMC to suit their setting, in-line with the current WHO recommendations for PMC. The Plus Project has partnered with governments and other key stakeholders to design country-specific models of PMC for their context, including the number and timing of SP doses as well as the delivery channel. In addition, the project has supported the formation of country Advisory and Technical Groups which are chaired by the government and meet regularly to review PMC implementation and research progress, discuss and address challenges, and keep country stakeholders up to speed with PMC activities. These same fora have been part of the transition planning to ensure the sustainability of the intervention after the Plus Project closes out.
Partners
The Unitaid-funded Plus Project is led by Population Services International (PSI) with the London School of Hygiene and Tropical Medicine (LSHTM) in collaboration with key government and research partners. Together, they support the co-design, implementation, and evaluation of different models of PMC, and complete activities aimed at supporting the adoption and scale-up of PMC within and beyond the focus countries.